pentobarbital will lessen the extent or effect of colchicine by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Observe.pentobarbital will lessen the level or result of bexarotene by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Observe.pentobarbital will reduce the extent or impact of irinotecan liposoma